What is the meaning of Ŭ?

Transliterates Malayalam , specifically word-finally, where it indicates /ɨ̆/.

A dictionary transcription for the STRUT vowel

The 22nd letter of the Belarusian Łacinka alphabet.

The twenty-sixth letter of the Esperanto alphabet, called ŭo and written in the Latin script.

The thirty-sixth letter of the Jarai alphabet, written in the Latin script.

Source: wiktionary.org