What is the meaning of Breakthrough?

Characterized by major progress or overcoming some obstacle.

Involving the contraction of a disease by a person with a decreased susceptibility, such as a person who has been vaccinated to help prevent that disease.

An advance through and past enemy lines.

Any major progress; such as a great innovation or discovery that overcomes a significant obstacle.

The penetration of the opposition's defence.

The penetration of a separating wall or the remaining distance to an adjacent hollow (a crosscut in mining) or between two parts of a tunnel build from both ends; knockthrough.

The emergence or one or more symptoms of a condition despite medication or other medical treatment.

Source: wiktionary.org